Ryan Gravenberch returns and Trey Nyoni starts as Andoni Iraola makes six changes for tonight’s Champions League clash with Villarreal at Anfield.
Gravenberch comes straight back into midfield after serving a one-match Premier League suspension in Saturday’s 2-1 win at Brentford, with Nyoni handed a start alongside him.
Kostas Tsimikas comes into the defence, while Cody Gakpo, Lewis Koumas and Rio Ngumoha are all named in the starting line-up.
Milos Kerkez, Florian Wirtz, Bradley Barcola and Alexander Isak drop to the bench after starting at Brentford, with only two days between the games. Iraola had hinted beforehand that his line-up might not be the one supporters expected, because some players were not fresh enough.
Dominik Szoboszlai and Jeremie Frimpong were already ruled out after both were forced off on Saturday, and Victor Munoz, who also started at Brentford, is not in the matchday squad.
Alisson, Ronald Araujo, Jeremy Jacquet, Virgil van Dijk and Alexis Mac Allister keep their places.
Academy youngsters Jayden Danns, James McConnell and Michael Laffey are among the substitutes, along with Joe Gomez and Luke Chambers.
Liverpool go into the game with six points from their opening two league-phase matches, after coming from behind to beat Atletico Madrid 2-1 at Anfield and winning 6-3 at LASK. Villarreal lost 3-2 at Borussia Dortmund before beating Napoli 3-1.
Liverpool starting XI: Alisson, Van Dijk, Jacquet, Mac Allister, Gakpo, Tsimikas, Araujo, Gravenberch, Nyoni, Koumas, Ngumoha.
Substitutes: Mamardashvili, Woodman, Gomez, Kerkez, Wirtz, Isak, Barcola, Chambers, McConnell, Danns, Laffey.
Kick-off at Anfield is at 8pm UK time, and the match is live on Prime Video.
