I'd worry having the 3 of them together because they are slight of frame and can easily be bullied off the ball. I'd be giving Origi a chance as the central attacker with Jota and Shaq on the flanks, bringing Minamino on later.
I'd have Neko Williams in for TAA and Milner in for Robbo, Curtis Jones in alongside Hendo and Wij and Alisson in goal:
Alisson
Williams Fabinho Gomez Milner
Jones Hendo Wij
Jota Origi Shaq
We should beat Midtjylland but let's not totally change it up. Fab and Gomez need gametime together for continuity seen as VVD is out for so long and Matip is still out injured. Get the game won then bring on Rhys Williams for one of the 2.
In the midfield we really don't have many options to give Hendo or Wij a rest so they must stay. Ditch the 4 pronged attack from the weekend and go with the 3 in midfield bringing in Curtis.
If it's going t.its up, have Bobby, Mane and Salah on the bench just in case.